Bioinformatics is the application of computer technology to the management of biological information.
The needs for Bioinformatics:
- Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied to gene-based drug discovery and development.
- Need for Bioinformatics capabilities has been precipitated by the explosion of publicly available genomic information resulting from the Human Genome Project.
- The science of Bioinformatics, which is the melding of molecular biology with computer science, is essential to the use of genomic information in understanding human diseases and in the identification of new molecular targets for drug discovery.
- Common activities in bioinformatics include mapping and analyzing DNA and protein sequences, aligning different DNA and protein sequences to compare them and creating and viewing 3D models of protein structures.
- The primary goal of bioinformatics is to increase our understanding of biological processes.
- Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions and the modeling of evolution.
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